Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

jak2a - Janus kinase 2a

Danio rerio

Synonyms: SO:0000704

Onnebo, S.M. et al., Oates, A.C. et al.

Oates, Brownlie, Pratt, Irvine, Liao, Paw, Dorian, Johnson, Postlethwait, Zon, Wilks,

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Disease relevance of jak2a

MATERIALS AND METHODS: To assess whether zebrafish could be utilized as a suitable model for the study of myeloid oncogenesis, we generated a zebrafish tel-jak2a fusion oncoprotein based on that seen in a case of chronic myeloid leukemia [1].

High impact information on jak2a

Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression patterns: only jak2a is expressed during erythropoiesis [2].
Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion [1].

References

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion. Onnebo, S.M., Condron, M.M., McPhee, D.O., Lieschke, G.J., Ward, A.C. Exp. Hematol. (2005) [Pubmed]
Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression patterns: only jak2a is expressed during erythropoiesis. Oates, A.C., Brownlie, A., Pratt, S.J., Irvine, D.V., Liao, E.C., Paw, B.H., Dorian, K.J., Johnson, S.L., Postlethwait, J.H., Zon, L.I., Wilks, A.F. Blood (1999) [Pubmed]

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