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Gene Review

sox3  -  SRY (sex determining region Y)-box 3

Danio rerio

Synonyms: SO:0000704, Transcription factor Sox-3, fc93f07, id:ibd2036, sb:cb493, ...
 
 
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High impact information on sox3

  • Knockdown of the d-Asb11 protein altered the expression of neural precursor genes sox2 and sox3 and resulted in an initial relative increase in proneural cell numbers [1].
  • By the one-somite stage, we saw a pair of single sox3-expressing domains appear lateral to the future hindbrain [2].
  • The expression of sox19a and sox3 begins at approximately the 1,000-cell stage during embryogenesis and becomes confined to the future ectoderm by the shield stage [3].

References

  1. The novel gene asb11: a regulator of the size of the neural progenitor compartment. Diks, S.H., Bink, R.J., van de Water, S., Joore, J., van Rooijen, C., Verbeek, F.J., den Hertog, J., Peppelenbosch, M.P., Zivkovic, D. J. Cell Biol. (2006) [Pubmed]
  2. Initial specification of the epibranchial placode in zebrafish embryos depends on the fibroblast growth factor signal. Nikaido, M., Doi, K., Shimizu, T., Hibi, M., Kikuchi, Y., Yamasu, K. Dev. Dyn. (2007) [Pubmed]
  3. Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution. Okuda, Y., Yoda, H., Uchikawa, M., Furutani-Seiki, M., Takeda, H., Kondoh, H., Kamachi, Y. Dev. Dyn. (2006) [Pubmed]
 
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