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Gene Review

raptor  -  CG4320 gene product from transcript CG4320-RC

Drosophila melanogaster

Synonyms: 4320, CG4320, Dmel\CG4320, Raptor, dRap, ...
 
 
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High impact information on raptor

  • Partially inhibiting dTOR/dRaptor signalling by dsRNAi or mild rapamycin treatment can increase cell number in cultured haemocytes and the Drosophila wing, respectively [1].
 

Anatomical context of raptor

  • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton [2].

References

  1. Insulin delays the progression of Drosophila cells through G2/M by activating the dTOR/dRaptor complex. Wu, M.Y., Cully, M., Andersen, D., Leevers, S.J. EMBO J. (2007) [Pubmed]
  2. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Sarbassov, D.D., Ali, S.M., Kim, D.H., Guertin, D.A., Latek, R.R., Erdjument-Bromage, H., Tempst, P., Sabatini, D.M. Curr. Biol. (2004) [Pubmed]
 
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