Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

pds - phytoene dehydrogenase

Synechococcus elongatus PCC 6301

Chamovitz, D. et al., Chamovitz, D. et al.

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Disease relevance of pds

We have cloned and sequenced a gene, pds, from the cyanobacterium Synechococcus PCC7942 that is responsible for resistance to the bleaching herbicide norflurazon [1].

High impact information on pds

Support for this conclusion is obtained from analysis of cells of an additional mutant strain, which overexpress phytoene desaturase due to a deletion mutation in the promoter region of pds [2].

References

The molecular basis of resistance to the herbicide norflurazon. Chamovitz, D., Pecker, I., Hirschberg, J. Plant Mol. Biol. (1991) [Pubmed]
Molecular and biochemical characterization of herbicide-resistant mutants of cyanobacteria reveals that phytoene desaturation is a rate-limiting step in carotenoid biosynthesis. Chamovitz, D., Sandmann, G., Hirschberg, J. J. Biol. Chem. (1993) [Pubmed]

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