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Gene Review

Tomosyn  -  Tomosyn ortholog

Drosophila melanogaster

Synonyms: BcDNA:RH19475, CG11056, CG17762, CG2205, Dmel\CG17762, ...
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High impact information on tomosyn

  • These proteins show significant similarity to the Drosophila tumor suppressor, lethal giant larvae and to the neuronal syntaxin-binding protein, tomosyn [1].
  • Taken together, these results indicate that rgl-1, not tomosyn, is the legitimate homologue of lgl gene [2].


  1. Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. Lehman, K., Rossi, G., Adamo, J.E., Brennwald, P. J. Cell Biol. (1999) [Pubmed]
  2. The rgl-1 is a legitimate homologue of lethal giant larvae recessive oncogene in rat. Kim, Y.S., Baek, K.H., Lee, K.Y., Chung, H.M., Lee, K.A., Ko, J.J., Cha, K.Y. Int. J. Oncol. (2002) [Pubmed]
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