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Gene Review

mbpa  -  myelin basic protein a

Danio rerio

Synonyms: SO:0000704, cb274, fj33b11, mbp, wu:fj33b11, ...
 
 
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High impact information on mbp

  • In addition, nsf mutants exhibit defects in Myelin basic protein expression and in localization of sodium channel proteins at nodes of Ranvier [1].
  • We found that addition of exogenous retinoic acid (RA) rescued mbp expression in neckless mutant embryos, which lack endogenous RA synthesis [2].
  • DM20 is expressed in the CNS only, while MBP transcripts are detected both in the CNS and in Schwann cells of the lateral line, cranial nerves, and spinal motor nerves [3].

References

  1. nsf is essential for organization of myelinated axons in zebrafish. Woods, I.G., Lyons, D.A., Voas, M.G., Pogoda, H.M., Talbot, W.S. Curr. Biol. (2006) [Pubmed]
  2. A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes. Kazakova, N., Li, H., Mora, A., Jessen, K.R., Mirsky, R., Richardson, W.D., Smith, H.K. Dev. Biol. (2006) [Pubmed]
  3. Characterization of myelination in the developing zebrafish. Brösamle, C., Halpern, M.E. Glia (2002) [Pubmed]
 
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