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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Schwann Cells

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Disease relevance of Schwann Cells


High impact information on Schwann Cells


Chemical compound and disease context of Schwann Cells


Biological context of Schwann Cells


Anatomical context of Schwann Cells


Associations of Schwann Cells with chemical compounds


Gene context of Schwann Cells


Analytical, diagnostic and therapeutic context of Schwann Cells


  1. Upregulation of class I major histocompatibility complex gene expression in primary sensory neurons, satellite cells, and Schwann cells of mice in response to acute but not latent herpes simplex virus infection in vivo. Pereira, R.A., Tscharke, D.C., Simmons, A. J. Exp. Med. (1994) [Pubmed]
  2. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. Yang, F.C., Ingram, D.A., Chen, S., Hingtgen, C.M., Ratner, N., Monk, K.R., Clegg, T., White, H., Mead, L., Wenning, M.J., Williams, D.A., Kapur, R., Atkinson, S.J., Clapp, D.W. J. Clin. Invest. (2003) [Pubmed]
  3. Type 1 neurofibromatosis: selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures. Jaakkola, S., Peltonen, J., Riccardi, V., Chu, M.L., Uitto, J. J. Clin. Invest. (1989) [Pubmed]
  4. Specific asparagine-linked oligosaccharides are not required for certain neuron-neuron and neuron-Schwann cell interactions. Ratner, N., Elbein, A., Bunge, M.B., Porter, S., Bunge, R.P., Glaser, L. J. Cell Biol. (1986) [Pubmed]
  5. Expression of recombinant myelin-associated glycoprotein in primary Schwann cells promotes the initial investment of axons by myelinating Schwann cells. Owens, G.C., Boyd, C.J., Bunge, R.P., Salzer, J.L. J. Cell Biol. (1990) [Pubmed]
  6. Role of the cell wall phenolic glycolipid-1 in the peripheral nerve predilection of Mycobacterium leprae. Ng, V., Zanazzi, G., Timpl, R., Talts, J.F., Salzer, J.L., Brennan, P.J., Rambukkana, A. Cell (2000) [Pubmed]
  7. Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons. Vogel, K.S., Brannan, C.I., Jenkins, N.A., Copeland, N.G., Parada, L.F. Cell (1995) [Pubmed]
  8. The peripheral myelin protein gene PMP-22 is contained within the Charcot-Marie-Tooth disease type 1A duplication. Timmerman, V., Nelis, E., Van Hul, W., Nieuwenhuijsen, B.W., Chen, K.L., Wang, S., Ben Othman, K., Cullen, B., Leach, R.J., Hanemann, C.O. Nat. Genet. (1992) [Pubmed]
  9. Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive. Winer, S., Tsui, H., Lau, A., Song, A., Li, X., Cheung, R.K., Sampson, A., Afifiyan, F., Elford, A., Jackowski, G., Becker, D.J., Santamaria, P., Ohashi, P., Dosch, H.M. Nat. Med. (2003) [Pubmed]
  10. Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A). Sereda, M.W., Meyer zu Hörste, G., Suter, U., Uzma, N., Nave, K.A. Nat. Med. (2003) [Pubmed]
  11. A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation. Ratner, N., Bunge, R.P., Glaser, L. J. Cell Biol. (1985) [Pubmed]
  12. Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development. Kramer, R., Bucay, N., Kane, D.J., Martin, L.E., Tarpley, J.E., Theill, L.E. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  13. Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells. Campana, W.M., Hiraiwa, M., O'Brien, J.S. FASEB J. (1998) [Pubmed]
  14. Schwann cell vulnerability to demyelination is associated with internodal length in tellurium neuropathy. Bouldin, T.W., Samsa, G., Earnhardt, T.S., Krigman, M.R. J. Neuropathol. Exp. Neurol. (1988) [Pubmed]
  15. Cell type-specific markers for human glial and neuronal cells in culture. Kennedy, P.G., Lisak, R.P., Raff, M.C. Lab. Invest. (1980) [Pubmed]
  16. Activation of the transcription factor NF-kappaB in Schwann cells is required for peripheral myelin formation. Nickols, J.C., Valentine, W., Kanwal, S., Carter, B.D. Nat. Neurosci. (2003) [Pubmed]
  17. Down-regulation of myelin-associated glycoprotein on Schwann cells by interferon-gamma and tumor necrosis factor-alpha affects neurite outgrowth. Schneider-Schaulies, J., Kirchhoff, F., Archelos, J., Schachner, M. Neuron (1991) [Pubmed]
  18. Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo. Friedman, B., Scherer, S.S., Rudge, J.S., Helgren, M., Morrisey, D., McClain, J., Wang, D.Y., Wiegand, S.J., Furth, M.E., Lindsay, R.M. Neuron (1992) [Pubmed]
  19. The protooncogene Ski controls Schwann cell proliferation and myelination. Atanasoski, S., Notterpek, L., Lee, H.Y., Castagner, F., Young, P., Ehrengruber, M.U., Meijer, D., Sommer, L., Stavnezer, E., Colmenares, C., Suter, U. Neuron (2004) [Pubmed]
  20. Neuron-glia cell adhesion molecule interacts with neurons and astroglia via different binding mechanisms. Grumet, M., Edelman, G.M. J. Cell Biol. (1988) [Pubmed]
  21. Trembler mouse carries a point mutation in a myelin gene. Suter, U., Welcher, A.A., Ozcelik, T., Snipes, G.J., Kosaras, B., Francke, U., Billings-Gagliardi, S., Sidman, R.L., Shooter, E.M. Nature (1992) [Pubmed]
  22. Krox-20 controls myelination in the peripheral nervous system. Topilko, P., Schneider-Maunoury, S., Levi, G., Baron-Van Evercooren, A., Chennoufi, A.B., Seitanidou, T., Babinet, C., Charnay, P. Nature (1994) [Pubmed]
  23. Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression. Jo, S.A., Zhu, X., Marchionni, M.A., Burden, S.J. Nature (1995) [Pubmed]
  24. Progesterone synthesis and myelin formation by Schwann cells. Koenig, H.L., Schumacher, M., Ferzaz, B., Thi, A.N., Ressouches, A., Guennoun, R., Jung-Testas, I., Robel, P., Akwa, Y., Baulieu, E.E. Science (1995) [Pubmed]
  25. Role of alpha-dystroglycan as a Schwann cell receptor for Mycobacterium leprae. Rambukkana, A., Yamada, H., Zanazzi, G., Mathus, T., Salzer, J.L., Yurchenco, P.D., Campbell, K.P., Fischetti, V.A. Science (1998) [Pubmed]
  26. Cyclic AMP as a mitogenic signal for cultured rat Schwann cells. Raff, M.C., Hornby-Smith, A., Brockes, J.P. Nature (1978) [Pubmed]
  27. Schwann cell galactocerebroside induced by derivatives of adenosine 3',5'-monophosphate. Sobue, G., Pleasure, D. Science (1984) [Pubmed]
  28. The claw paw mutation reveals a role for Lgi4 in peripheral nerve development. Bermingham, J.R., Shearin, H., Pennington, J., O'Moore, J., Jaegle, M., Driegen, S., van Zon, A., Darbas, A., Ozkaynak, E., Ryu, E.J., Milbrandt, J., Meijer, D. Nat. Neurosci. (2006) [Pubmed]
  29. Cultured Schwann cells constitutively express the myelin protein P0. Cheng, L., Mudge, A.W. Neuron (1996) [Pubmed]
  30. Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75. Carter, B.D., Kaltschmidt, C., Kaltschmidt, B., Offenhäuser, N., Böhm-Matthaei, R., Baeuerle, P.A., Barde, Y.A. Science (1996) [Pubmed]
  31. The transcription factor Sox10 is a key regulator of peripheral glial development. Britsch, S., Goerich, D.E., Riethmacher, D., Peirano, R.I., Rossner, M., Nave, K.A., Birchmeier, C., Wegner, M. Genes Dev. (2001) [Pubmed]
  32. Nab proteins are essential for peripheral nervous system myelination. Le, N., Nagarajan, R., Wang, J.Y., Svaren, J., LaPash, C., Araki, T., Schmidt, R.E., Milbrandt, J. Nat. Neurosci. (2005) [Pubmed]
  33. Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma. Hirota, H., Kiyama, H., Kishimoto, T., Taga, T. J. Exp. Med. (1996) [Pubmed]
  34. Schwann cells infected with a recombinant retrovirus expressing myelin-associated glycoprotein antisense RNA do not form myelin. Owens, G.C., Bunge, R.P. Neuron (1991) [Pubmed]
  35. Studies of Schwann cell proliferation. II. Characterization of the stimulation and specificity of the response to a neurite membrane fraction. Salzer, J.L., Williams, A.K., Glaser, L., Bunge, R.P. J. Cell Biol. (1980) [Pubmed]
  36. Identification of a lipid-anchored heparan sulfate proteoglycan in Schwann cells. Carey, D.J., Stahl, R.C. J. Cell Biol. (1990) [Pubmed]
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