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Gene Review

e(y)3  -  enhancer of yellow 3

Drosophila melanogaster

Synonyms: CG12238, Dmel\CG12238, Protein enhancer of yellow 3, SAYP, Supporter of activation of yellow protein, ...
 
 
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High impact information on l(1)G0084

  • A novel multidomain transcription coactivator SAYP can also repress transcription in heterochromatin [1].
  • SAYP binds to numerous sites of transcriptionally active euchromatin on polytene chromosomes and coactivates transcription of euchromatin genes [1].
  • In addition, we found that mutations in the e(y)1, e(y)3 and zeste genes may interfere with transcriptional insulation by the su(Hw)-binding region in the scD1 allele [2].

References

  1. A novel multidomain transcription coactivator SAYP can also repress transcription in heterochromatin. Shidlovskii, Y.V., Krasnov, A.N., Nikolenko, J.V., Lebedeva, L.A., Kopantseva, M., Ermolaeva, M.A., Ilyin, Y.V., Nabirochkina, E.N., Georgiev, P.G., Georgieva, S.G. EMBO J. (2005) [Pubmed]
  2. Phenotypic reversion of the gypsy-induced mutation scD1 of Drosophila melanogaster by replicative transposition of a sc enhancer to the yellow gene and by mutations in the enhancer of yellow and zeste loci. Gause, M., Georgieva, S., Georgiev, P. Mol. Gen. Genet. (1996) [Pubmed]
 
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