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Gene Review:

HSPA6 - heat shock 70kDa protein 6 (HSP70B')

Homo sapiens

Synonyms: HSP70B', Heat shock 70 kDa protein 6, Heat shock 70 kDa protein B'

Leung, T.K. et al., Wang, M.M. et al., Lomholt, B. et al.

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High impact information on HSPA6

Recovered populations were verified to be both viable and unstressed by evaluation of the transcriptional expression of two genes, HSPA6 and FOS, known indicators of cellular stress [1].
The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1 [2].
Porcine 5S rRNA genes map to 14q23 revealing syntenic relation to human HSPA6- and 7 [3].

Other interactions of HSPA6

Both HSPA6 and HSPA7 represent functional genes, as determined by analyses of mRNA from heat-shocked human cells using specific oligonucleotides, although their pattern of expression differed [2].

References

Microfluidic sorting of mammalian cells by optical force switching. Wang, M.M., Tu, E., Raymond, D.E., Yang, J.M., Zhang, H., Hagen, N., Dees, B., Mercer, E.M., Forster, A.H., Kariv, I., Marchand, P.J., Butler, W.F. Nat. Biotechnol. (2005) [Pubmed]
The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1. Leung, T.K., Hall, C., Rajendran, M., Spurr, N.K., Lim, L. Genomics (1992) [Pubmed]
Porcine 5S rRNA genes map to 14q23 revealing syntenic relation to human HSPA6- and 7. Lomholt, B., Christensen, K., Hallenberg, C., Frederiksen, S. Mamm. Genome (1995) [Pubmed]

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