The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia
  • UniProt

Table of contents

About

Terms

 

Gene Review: 

tty  -  tweety

Drosophila melanogaster

Synonyms: CG1693, Dmel\CG1693, Dttyh1, Protein tweety, TTYH1, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of tty

 

High impact information on tty

  • We report here that tweety, a gene located in Drosophila flightless, has a structure similar to those of known channels and that human homologues of tweety (hTTYH1-3) are novel maxi-Cl(-) channels. hTTYH3 mRNA was found to be distributed in excitable tissues [2].
  • I conclude that investigation of the tweety family will provide important information about large-conductance Cl- channel molecules [3].

References

  1. TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma. Rae, F.K., Hooper, J.D., Eyre, H.J., Sutherland, G.R., Nicol, D.L., Clements, J.A. Genomics (2001) [Pubmed]
  2. A novel human Cl(-) channel family related to Drosophila flightless locus. Suzuki, M., Mizuno, A. J. Biol. Chem. (2004) [Pubmed]
  3. The Drosophila tweety family: molecular candidates for large-conductance Ca2+-activated Cl- channels. Suzuki, M. Exp. Physiol. (2006) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities