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Gene Review:

ompA - major outer membrane protein precursor

Chlamydophila abortus S26/3

Iwamoto, K. et al., Mochizuki, M. et al., Di Francesco, A. et al., Sykes, J.E. et al.

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Disease relevance of ompA

Comparison of Chlamydia psittaci from cats with upper respiratory tract disease by polymerase chain reaction analysis of the ompA gene [1].
Chlamydia psittaci, examined by a PCR assay amplifying the ompA gene, was found in 26.9% of 26 diseased cats that typically showed conjunctivitis and rhinitis [2].

High impact information on ompA

The PCR products from positive samples for ompA and groEL genes were digested with the restriction enzyme Alu I and Hind III, respectively [3].
Comparison of nucleotide sequences of the ompA gene amplified from the three isolates with the published sequence of feline FEPN strain of C. psittaci showed almost 100% homology [4].

References

Comparison of Chlamydia psittaci from cats with upper respiratory tract disease by polymerase chain reaction analysis of the ompA gene. Sykes, J.E., Studdert, V.P., Anderson, G., Browning, G.F. Vet. Rec. (1997) [Pubmed]
Recent epidemiological status of feline upper respiratory infections in Japan. Mochizuki, M., Kawakami, K., Hashimoto, M., Ishida, T. J. Vet. Med. Sci. (2000) [Pubmed]
Feline chlamydiosis in Italy: PCR amplification and analysis of the ompA and groEL-homolog genes. Di Francesco, A., Baldelli, R. New Microbiol. (2002) [Pubmed]
Isolation of chlamydia psittaci from domestic cats with oculonasal discharge in Japan. Iwamoto, K., Masubuchi, K., Nosaka, H., Kokubu, T., Nishida, K., Toshida, T., Yamanaka, M. J. Vet. Med. Sci. (2001) [Pubmed]

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