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MeSH Review


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Disease relevance of Conjunctivitis


Psychiatry related information on Conjunctivitis


High impact information on Conjunctivitis


Chemical compound and disease context of Conjunctivitis


Biological context of Conjunctivitis

  • In the first girl with ligneous conjunctivitis a homozygous G-->A point mutation was identified in plasminogen exon 7 at position 780 leading to an amino acid exchange (Arg216-->His) [15].
  • METHODS: Between 1972 and 1993, 17 patients with ligneous conjunctivitis were treated with excision biopsy, meticulous hemostasis, and immediate, intensive topical treatment with heparin, steroids, and, in 12 patients, alpha-chymotrypsin until all signs of conjunctival inflammation had subsided [16].
  • Familial cold autoinflammatory syndrome (FCAS) is an autosomal dominant inflammatory disease with a high degree of penetrance that is characterized by episodes of rash, arthralgia, fever, conjunctivitis, and leukocytosis after generalized exposure to cold [17].
  • Compound 48/80-induced conjunctivitis in the mouse: kinetics, susceptibility, and mechanism [18].
  • In vivo, 1% Pred Forte significantly reduced conjunctivitis (P = .04) and subepithelial infiltrates (P = .02), but enhanced viral replication (P = .01) on days 9 to 21 and increased the duration of viral shedding (P < .001) [19].

Anatomical context of Conjunctivitis


Gene context of Conjunctivitis


Analytical, diagnostic and therapeutic context of Conjunctivitis


  1. Erythromycin ointment for ocular prophylaxis of neonatal chlamydial infection. Hammerschlag, M.R., Chandler, J.W., Alexander, E.R., English, M., Chiang, W.T., Koutsky, L., Eschenbach, D.A., Smith, J.R. JAMA (1980) [Pubmed]
  2. Severe TNF receptor-associated periodic syndrome due to 2 TNFRSF1A mutations including a new F60V substitution. Haas, S.L., Lohse, P., Schmitt, W.H., Hildenbrand, R., Karaorman, M., Singer, M.V., Böcker, U. Gastroenterology (2006) [Pubmed]
  3. High-dose cytosine arabinoside therapy for refractory leukemia. Herzig, R.H., Wolff, S.N., Lazarus, H.M., Phillips, G.L., Karanes, C., Herzig, G.P. Blood (1983) [Pubmed]
  4. Lymphocyte proliferation response to extracts from different latex materials and to the purified latex allergen Hev b 1 (rubber elongation factor). Raulf-Heimsoth, M., Chen, Z., Liebers, V., Allmers, H., Baur, X. J. Allergy Clin. Immunol. (1996) [Pubmed]
  5. Induction of late cutaneous reactions by skin-blister fluid from allergen-tested and normal skin. Dorsch, W., Ring, J. J. Allergy Clin. Immunol. (1981) [Pubmed]
  6. Mulvihill-Smith syndrome: case report and review. Bartsch, O., Tympner, K.D., Schwinger, E., Gorlin, R.J. J. Med. Genet. (1994) [Pubmed]
  7. Generalised Listeria monocytogenes infection in a dog. Schroeder, H., van Rensburg, I.B. Journal of the South African Veterinary Association. (1993) [Pubmed]
  8. Therapy with a purified plasminogen concentrate in an infant with ligneous conjunctivitis and homozygous plasminogen deficiency. Schott, D., Dempfle, C.E., Beck, P., Liermann, A., Mohr-Pennert, A., Goldner, M., Mehlem, P., Azuma, H., Schuster, V., Mingers, A.M., Schwarz, H.P., Kramer, M.D. N. Engl. J. Med. (1998) [Pubmed]
  9. A controlled trial of povidone-iodine as prophylaxis against ophthalmia neonatorum. Isenberg, S.J., Apt, L., Wood, M. N. Engl. J. Med. (1995) [Pubmed]
  10. Efficacy of neonatal ocular prophylaxis for the prevention of chlamydial and gonococcal conjunctivitis. Hammerschlag, M.R., Cummings, C., Roblin, P.M., Williams, T.H., Delke, I. N. Engl. J. Med. (1989) [Pubmed]
  11. The spectrum of IgE-mediated responses to latex. Sussman, G.L., Tarlo, S., Dolovich, J. JAMA (1991) [Pubmed]
  12. Conjunctivitis due to ketoprofen. Umez-Eronini, E.M. Lancet (1978) [Pubmed]
  13. Aerosolized pentamidine and conjunctivitis. Lindley, D.A., Schleupner, C.J. Ann. Intern. Med. (1988) [Pubmed]
  14. Conjunctivitis associated with methicillin-resistant Staphylococcus aureus in a long-term-care facility. Brennen, C., Muder, R.R. Am. J. Med. (1990) [Pubmed]
  15. Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis. Schuster, V., Mingers, A.M., Seidenspinner, S., Nüssgens, Z., Pukrop, T., Kreth, H.W. Blood (1997) [Pubmed]
  16. Topical heparin in the treatment of ligneous conjunctivitis. De Cock, R., Ficker, L.A., Dart, J.G., Garner, A., Wright, P. Ophthalmology (1995) [Pubmed]
  17. Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P. Hoffman, H.M., Gregory, S.G., Mueller, J.L., Tresierras, M., Broide, D.H., Wanderer, A.A., Kolodner, R.D. Hum. Genet. (2003) [Pubmed]
  18. Compound 48/80-induced conjunctivitis in the mouse: kinetics, susceptibility, and mechanism. Li, Q., Luyo, D., Hikita, N., Whitcup, S.M., Chan, C.C. Int. Arch. Allergy Immunol. (1996) [Pubmed]
  19. The effects of corticosteroids of adenoviral replication. Romanowski, E.G., Roba, L.A., Wiley, L., Araullo-Cruz, T., Gordon, Y.J. Arch. Ophthalmol. (1996) [Pubmed]
  20. Contraceptive pills induce an improvement in congenital hypoplasminogenemia in two unrelated patients with ligneous conjunctivitis. Teresa Sartori, M., Saggiorato, G., Pellati, D., Casonato, A., Spiezia, L., Pontara, E., Gavasso, S., Girolami, A. Thromb. Haemost. (2003) [Pubmed]
  21. Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis. Zinchuk, O., Fukushima, A., Zinchuk, V., Fukata, K., Ueno, H. Mol. Vis. (2005) [Pubmed]
  22. Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models. Spangler, D.L., Abelson, M.B., Ober, A., Gotnes, P.J. Clinical therapeutics. (2003) [Pubmed]
  23. Allergen-induced interleukin-9 production in vitro: correlation with atopy in human adults and comparison with interleukin-5 and interleukin-13. Devos, S., Cormont, F., Vrtala, S., Hooghe-Peters, E., Pirson, F., Snick, J. Clin. Exp. Allergy (2006) [Pubmed]
  24. Plasminogen and tissue-type plasminogen activator deficiency as risk factors for thromboembolic disease. Brandt, J.T. Arch. Pathol. Lab. Med. (2002) [Pubmed]
  25. Expression of gelatinase B in trachomatous conjunctivitis. El-Asrar, A.M., Geboes, K., Al-Kharashi, S.A., Al-Mosallam, A.A., Missotten, L., Paemen, L., Opdenakker, G. The British journal of ophthalmology. (2000) [Pubmed]
  26. Involvement of cyclooxygenase-2 in rat models of conjunctivitis. Oka, T., Shearer, T., Azuma, M. Curr. Eye Res. (2004) [Pubmed]
  27. Levocabastine. An update of its pharmacology, clinical efficacy and tolerability in the topical treatment of allergic rhinitis and conjunctivitis. Noble, S., McTavish, D. Drugs (1995) [Pubmed]
  28. Epidemiology of otitis media onset by six months of age. Daly, K.A., Brown, J.E., Lindgren, B.R., Meland, M.H., Le, C.T., Giebink, G.S. Pediatrics (1999) [Pubmed]
  29. Double-blind, placebo-controlled evaluation of sublingual immunotherapy with standardized olive pollen extract in pediatric patients with allergic rhinoconjunctivitis and mild asthma due to olive pollen sensitization. Vourdas, D., Syrigou, E., Potamianou, P., Carat, F., Batard, T., André, C., Papageorgiou, P.S. Allergy (1998) [Pubmed]
  30. Effect of oral administration of L-lysine on conjunctivitis caused by feline herpesvirus in cats. Stiles, J., Townsend, W.M., Rogers, Q.R., Krohne, S.G. Am. J. Vet. Res. (2002) [Pubmed]
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