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Gene Review:

algL - poly(beta-D-mannuronate) lyase

Pseudomonas syringae pv. syringae B728a

Preston, L.A. et al., Peñaloza-Vázquez, A. et al., Preston, L.A. et al.

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Disease relevance of algL

The gene encoding alginate lyase (algL) in Pseudomonas syringae pv. syringae was cloned, sequenced, and overexpressed in Escherichia coli [1].

High impact information on algL

A cosmid clone designated pSK2 restored alginate production to the algL mutant and was shown to contain homologs of algD, alg8, alg44, algG, algX (alg60), algL, algF, and algA [2].
Analysis of the regions flanking algL revealed significant homology to algX and algI, genes previously identified in the biosynthetic operon of other alginate-producing bacteria [3].

References

Characterization of alginate lyase from Pseudomonas syringae pv. syringae. Preston, L.A., Wong, T.Y., Bender, C.L., Schiller, N.L. J. Bacteriol. (2000) [Pubmed]
Characterization of the alginate biosynthetic gene cluster in Pseudomonas syringae pv. syringae. Peñaloza-Vázquez, A., Kidambi, S.P., Chakrabarty, A.M., Bender, C.L. J. Bacteriol. (1997) [Pubmed]
Analysis and expression of algL, which encodes alginate lyase in Pseudomonas syringae Pv. syringae. Preston, L.A., Bender, C.L., Schiller, N.L. DNA Seq. (2001) [Pubmed]

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