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Gene Review: 

Rack1  -  Receptor of activated protein kinase C 1

Drosophila melanogaster

Synonyms: CG7111, Dmel\CG7111, Guanine nucleotide-binding protein subunit beta-like protein, RACK1, Receptor of activated protein kinase C homolog, ...
 
 
 
 
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High impact information on Rack1

  • The Drosophila rack1 gene has a dynamic pattern of expression during early embryogenesis with the highest expression in the mesodermal and endodermal lineages [1].
  • The mammalian RACK1 protein binds activated protein kinase C, acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton [1].

References

  1. Isolation and cloning of a Drosophila homolog to the mammalian RACK1 gene, implicated in PKC-mediated signalling. Vani, K., Yang, G., Mohler, J. Biochim. Biophys. Acta (1997) [Pubmed]
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