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Gene Review

PKD1L3  -  polycystic kidney disease 1-like 3

Homo sapiens

Synonyms: PC1-like 3 protein, Polycystic kidney disease protein 1-like 3, Polycystin-1L3
 
 
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High impact information on PKD1L3

 

Other interactions of PKD1L3

  • PKD1L2 and PKD1L3 contain strong ion channel signature motifs that suggest their possible function as components of cation channel pores [2].
  • Finally, PKD1L3 and PKD2L1 are activated by various acids when coexpressed in heterologous cells but not by other classes of tastants [1].

References

  1. Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. Ishimaru, Y., Inada, H., Kubota, M., Zhuang, H., Tominaga, M., Matsunami, H. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  2. Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes. Li, A., Tian, X., Sung, S.W., Somlo, S. Genomics (2003) [Pubmed]
 
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