Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

htrB - heat shock protein B

Haemophilus influenzae 86-028NP

Swords, W.E. et al., Starner, T.D. et al.

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Disease relevance of htrB

Acylation of the lipooligosaccharide of Haemophilus influenzae and colonization: an htrB mutation diminishes the colonization of human airway epithelial cells [1].

High impact information on htrB

Complementation by htrB in trans to acylation competence reversed this increased sensitivity [2].

Analytical, diagnostic and therapeutic context of htrB

Inoculation of human bronchiolar xenografts revealed a significant reduction in colonization capacity by htrB mutants [1].

References

Acylation of the lipooligosaccharide of Haemophilus influenzae and colonization: an htrB mutation diminishes the colonization of human airway epithelial cells. Swords, W.E., Chance, D.L., Cohn, L.A., Shao, J., Apicella, M.A., Smith, A.L. Infect. Immun. (2002) [Pubmed]
Susceptibility of nontypeable Haemophilus influenzae to human beta-defensins is influenced by lipooligosaccharide acylation. Starner, T.D., Swords, W.E., Apicella, M.A., McCray, P.B. Infect. Immun. (2002) [Pubmed]

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