Gene Review:
Sir2 - CG5216 gene product from transcript CG5216-RA
Drosophila melanogaster
Synonyms:
BEST:LD38188, CG5216, D.mel1, DSir2, Dmel\CG5216, ...
- Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination. Rosenberg, M.I., Parkhurst, S.M. Cell (2002)
- dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster. Barlow, A.L., van Drunen, C.M., Johnson, C.A., Tweedie, S., Bird, A., Turner, B.M. Exp. Cell Res. (2001)
- A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span. Newman, B.L., Lundblad, J.R., Chen, Y., Smolik, S.M. Genetics (2002)
- Reconstitution of chromatin transcription with purified components reveals a chromatin-specific repressive activity of p300. Santoso, B., Kadonaga, J.T. Nat. Struct. Mol. Biol. (2006)
- Drosophila longevity is not affected by heterochromatin-mediated gene silencing. Frankel, S., Rogina, B. Aging Cell (2005)