High impact information on osp

• As defined by these and other breakpoints, the osp gene spans at least 52 X 10(3) base-pairs and overlaps the Adh gene [1].
• Experimental analyses of in vivo processing intermediates and lariat products from four large introns in the unrelated genes kuzbanian, outspread, and Ultrabithorax confirmed that these introns are removed by a series of recursive splicing steps using the predicted nonexonic sites [2].
• The osp cDNAs comprise two distinct classes based on alternative splicing patterns [3].
• In the ovary, osp is transcribed in nurse cells and localized in the oocyte [3].
• In addition, three visible phenotypes have been defined only by overlapping deficiencies (melanized-like, tumorous head, and varied outspread) [4].

Analytical, diagnostic and therapeutic context of osp

• In situ hybridization shows that osp is expressed both maternally and zygotically [3].

References