Gene Review:
Ac3 - CG1506 gene product from transcript CG1506-RA
Drosophila melanogaster
Synonyms:
AC 3, AC3, CG1506, DAC3, DAC39E, ...
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High impact information on Ac3
- DAC39E catalytic activity is inhibited by micromolar concentrations of calcium; therefore, DAC39E is oppositely regulated by calcium compared to the only other tmAC shown to be expressed in the Drosophila CNS, Rutabaga AC [1].
- DAC39E protein sequence is most closely related to mammalian type III AC, and it is predominantly expressed in the central nervous system (CNS) and olfactory organs, suggesting a role in processing sensory signaling inputs [1].
References
- A calcium-inhibited Drosophila adenylyl cyclase. Iourgenko, V., Levin, L.R. Biochim. Biophys. Acta (2000) [Pubmed]
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