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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Pabp2  -  CG2163 gene product from transcript CG2163-RA

Drosophila melanogaster

Synonyms: CG2163, Dmel\CG2163, Nuclear poly(A)-binding protein 1, PABII, PABP-2, ...
 
 
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High impact information on Pabp2

  • Hence, we have herein applied degenerate polymerase chain reaction (PCR) methodology to clone three additional members (termed rox2, rox8 and rox21) of the D. melanogaster RRM-protein gene superfamily encoding putative trans-acting regulatory factors [1].
  • PABP2 is required in vivo for polyadenylation, and Pabp2 function, including poly(A) polymerase stimulation, is essential for viability [2].

References

  1. Novel Drosophila melanogaster genes encoding RRM-type RNA-binding proteins identified by a degenerate PCR strategy. Brand, S.F., Pichoff, S., Noselli, S., Bourbon, H.M. Gene (1995) [Pubmed]
  2. An essential cytoplasmic function for the nuclear poly(A) binding protein, PABP2, in poly(A) tail length control and early development in Drosophila. Benoit, B., Mitou, G., Chartier, A., Temme, C., Zaessinger, S., Wahle, E., Busseau, I., Simonelig, M. Dev. Cell (2005) [Pubmed]
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