The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

fgf24  -  fibroblast growth factor 24

Danio rerio

Synonyms: SI:zC207O21.2, SO:0000704, lbx1h, si:zc207o21.1
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on fgf24


Anatomical context of fgf24

  • We found that inhibiting fgf24 function alone has no affect on the formation of posterior mesoderm [1].


Evolutionary origin

Phylogenetic analysis of fgf24 suggests it belongs to the Fgf8/17/18 family of genes that diversified through duplication in the vertebrate lineage. fgf24 has only been identified so far in teleost fish. However, comparative genomics suggests that, rather being a fish specific duplication, fgf24 is an ohnolog (one of the paralogs produced via whole genome duplication) lost from other vertebrate genomes [3]


  1. Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development. Draper, B.W., Stock, D.W., Kimmel, C.B. Development (2003) [Pubmed]
  2. The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation. Fischer, S., Draper, B.W., Neumann, C.J. Development (2003) [Pubmed]
  3. Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates. Wotton, K.R., Weierud, F.K., Dietrich, S., Lewis, K.E. BMC. Evol. Biol. (2008) [Pubmed]
WikiGenes - Universities