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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Angptl4  -  angiopoietin-like 4

Rattus norvegicus

Synonyms: Angiopoietin-like protein 4, Angiopoietin-related protein 4, HFARP, Hepatic fibrinogen/angiopoietin-related protein
 
 
 
 
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High impact information on Angptl4

  • Angiopoietin-like protein 4 (Angptl4) is a recently identified circulating protein expressed primarily in adipose tissue and liver [1].
  • Treatments with various ligands of nuclear receptors reveal that Angptl3 is a target gene of liver X receptor, while Angptl4 expression is activated by ligands of all peroxisome proliferator-activated receptors [2].

References

  1. Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4. Ge, H., Yang, G., Huang, L., Motola, D.L., Pourbahrami, T., Li, C. J. Biol. Chem. (2004) [Pubmed]
  2. Differential regulation and properties of angiopoietin-like proteins 3 and 4. Ge, H., Cha, J.Y., Gopal, H., Harp, C., Yu, X., Repa, J.J., Li, C. J. Lipid Res. (2005) [Pubmed]
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