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Gene Review

Havcr2  -  hepatitis A virus cellular receptor 2

Rattus norvegicus

Synonyms: HAVcr-2, Hepatitis A virus cellular receptor 2 homolog, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, ...
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High impact information on Havcr2

  • However, expression of TIM-1 and -3 is not restricted solely to T cells and the presence of TIM-3 in resident CNS cells may indicate a role for this molecule in the interaction between the nervous and immune systems [1].
  • TIM-3 expression was upregulated in the spinal cord during EAE and following antigen restimulation of the encephalitogenic TCRBV8S2+ population [1].

Analytical, diagnostic and therapeutic context of Havcr2


  1. Expression of T cell immunoglobulin- and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems. Gielen, A.W., Lobell, A., Lidman, O., Khademi, M., Olsson, T., Piehl, F. J. Neuroimmunol. (2005) [Pubmed]
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