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Gene Review:

sctR - type III secretion system protein

Chlamydia trachomatis A/HAR-13

Muschiol, S. et al., Bavoil, P.M. et al.

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Disease relevance of sctR

The intracellular pathogen Chlamydia trachomatis possesses a type III secretion (TTS) system believed to deliver a series of effector proteins into the inclusion membrane (Inc-proteins) as well as into the host cytosol with perceived consequences for the pathogenicity of this common venereal pathogen [1].
Recently, small molecules were shown to block the TTS system of Yersinia pseudotuberculosis [1].

Psychiatry related information on sctR

Type III secretion in Chlamydia: a case of déjà vu [2]?

References

A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis. Muschiol, S., Bailey, L., Gylfe, A., Sundin, C., Hultenby, K., Bergstr??m, S., Elofsson, M., Wolf-Watz, H., Normark, S., Henriques-Normark, B. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
Type III secretion in Chlamydia: a case of déjà vu? Bavoil, P.M., Hsia, R.C. Mol. Microbiol. (1998) [Pubmed]

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