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Gene Review:

sqdC - putative sulfolipid biosynthesis protein

Rhodobacter sphaeroides 2.4.1

Rossak, M. et al., Benning, C. et al.

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Disease relevance of sqdC

Accumulation of sulfoquinovosyl-1-O-dihydroxyacetone in a sulfolipid-deficient mutant of Rhodobacter sphaeroides inactivated in sqdC [1].

High impact information on sqdC

Sequence analysis of the relevant region of the clone revealed three, in tandem open reading frames, designated sqdB, ORF2, and sqdC [2].
Based on our results we propose that the sqdC gene product mediates the substrate specificity of the UDP-sulfoquinovose:diacylglycerol sulfoquinovosyltransferase that is encoded by sqdD and that catalyzes the final reaction of sulfolipid biosynthesis [1].

References

Accumulation of sulfoquinovosyl-1-O-dihydroxyacetone in a sulfolipid-deficient mutant of Rhodobacter sphaeroides inactivated in sqdC. Rossak, M., Schäfer, A., Xu, N., Gage, D.A., Benning, C. Arch. Biochem. Biophys. (1997) [Pubmed]
Identification of an operon involved in sulfolipid biosynthesis in Rhodobacter sphaeroides. Benning, C., Somerville, C.R. J. Bacteriol. (1992) [Pubmed]

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