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Gene Review

sqdD  -  glycosyl transferase (sulfolipid...

Rhodobacter sphaeroides 2.4.1

 
 
 
 
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Disease relevance of sqdD

  • The biosynthesis of the sulfolipid sulfoquinovosyl diacylglycerol in the purple bacterium Rhodobacter sphaeroides requires at least four genes:sqdA, sqdB, sqdC, and sqdD [1].
 

High impact information on sqdD

  • Based on our results we propose that the sqdC gene product mediates the substrate specificity of the UDP-sulfoquinovose:diacylglycerol sulfoquinovosyltransferase that is encoded by sqdD and that catalyzes the final reaction of sulfolipid biosynthesis [1].

References

  1. Accumulation of sulfoquinovosyl-1-O-dihydroxyacetone in a sulfolipid-deficient mutant of Rhodobacter sphaeroides inactivated in sqdC. Rossak, M., Schäfer, A., Xu, N., Gage, D.A., Benning, C. Arch. Biochem. Biophys. (1997) [Pubmed]
 
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