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Gene Review

RpL11  -  Ribosomal protein L11

Drosophila melanogaster

Synonyms: 60S ribosomal protein L11, BcDNA:LD17235, CG7726, DL11, Dmel\CG7726, ...
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Disease relevance of RpL11

  • One of the two yeast proteins, protein YL23, seems to be very well preserved during evolution, since antisera specific for YL23 cross-react with protein EC L11 from Escherichia coli [1].

High impact information on RpL11

  • These proteins, L10/L11, L26, S1/S4, S13, and S20, are likely present in the binding site of the 3' end of peptidyl-tRNA, a site that appears to span both subunits [2].
  • However, in contrast to protein EC L11, protein YL23 interacts with the yeast acidic proteins, forming a complex probably similar to the one made by bacterial protein EC L10 with proteins EC L7 and EC L12 in the E. coli ribosome [1].

Analytical, diagnostic and therapeutic context of RpL11


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