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Gene Review:

MED16 - Mediator complex subunit 16

Drosophila melanogaster

Synonyms: CG5465, Dmel\CG5465, Med16, Mediator of RNA polymerase II transcription subunit 16, Sin4/TRAP95, ...

Kim, T.W. et al.

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High impact information on MED16

In particular, MED16 and MED23 were required for lipopolysaccharide- and heat-shock-specific gene expression, respectively, and their activator-specific functions appeared to result from interaction with specific activators [1].

Associations of MED16 with chemical compounds

MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators [1].

Analytical, diagnostic and therapeutic context of MED16

The corequirement of MED16 for other forms of differentiation-inducing factor-induced transcription was confirmed by microarray analysis of differentiation-inducing factor (DIF)- and MED16-depleted cells individually [1].

References

MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators. Kim, T.W., Kwon, Y.J., Kim, J.M., Song, Y.H., Kim, S.N., Kim, Y.J. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

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