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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

kcp  -  kielin/chordin-like protein

Xenopus laevis

 
 
 
 
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High impact information on LOC378806

  • Unlike Chd, Kielin does not efficiently induce neural differentiation of animal cap ectoderm, suggesting that the activity of Kielin is not simply caused by BMP4 blockade [1].
  • Kielin is induced in mesoderm and in ectoderm by nodal-related genes [1].
  • Expression of Kielin starts at midgastrula stages in the notochord and is detected in the floor plate of neurula embryos [1].

References

  1. Xenopus kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline. Matsui, M., Mizuseki, K., Nakatani, J., Nakanishi, S., Sasai, Y. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
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