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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

slik  -  Sterile20-like kinase

Drosophila melanogaster

Synonyms: CG4527, DPlkk1, Dmel\CG4527, PLKK1, Plkk/Slik, ...
 
 
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High impact information on slik

  • The abnormal behavior of slik mutant cells is due to failure to phosphorylate and activate Moesin, which leads to excess Rho1 activity [1].
  • The Drosophila sterile-20 kinase slik controls cell proliferation and apoptosis during imaginal disc development [2].

References

  1. Slik Sterile-20 kinase regulates Moesin activity to promote epithelial integrity during tissue growth. Hipfner, D.R., Keller, N., Cohen, S.M. Genes Dev. (2004) [Pubmed]
  2. The Drosophila sterile-20 kinase slik controls cell proliferation and apoptosis during imaginal disc development. Hipfner, D.R., Cohen, S.M. PLoS Biol. (2003) [Pubmed]
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