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Gene Review

LysD  -  Lysozyme D

Drosophila melanogaster

Synonyms: CG9118, Dmel\CG9118, lysD
 
 
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High impact information on LysD

  • The LysD-like genes and LysS are strongly repressed in artificially infected animals, possibly reflecting a malaise reaction in the digestive tract [1].
  • The locus was mapped to the cytological location 61F1-4 on the third chromosome and two of the genes at this locus, LysD and LysP, were analyzed in detail [2].
  • The most remarkable sequence convergence of D. melanogaster lysozyme D and lysozymes from vertebrate foregut fermenters are serine 104 and a decrease in the number of basic amino acids, suggesting that these features are necessary for digestive function in an acid environment [3].

References

  1. The lysozyme locus in Drosophila melanogaster: an expanded gene family adapted for expression in the digestive tract. Daffre, S., Kylsten, P., Samakovlis, C., Hultmark, D. Mol. Gen. Genet. (1994) [Pubmed]
  2. The lysozyme locus in Drosophila melanogaster: different genes are expressed in midgut and salivary glands. Kylsten, P., Kimbrell, D.A., Daffre, S., Samakovlis, C., Hultmark, D. Mol. Gen. Genet. (1992) [Pubmed]
  3. Molecular adaptation of Drosophila melanogaster lysozymes to a digestive function. Regel, R., Matioli, S.R., Terra, W.R. Insect Biochem. Mol. Biol. (1998) [Pubmed]
 
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