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Gene Review

Awh  -  Arrowhead

Drosophila melanogaster

Synonyms: CG1072, Dmel\CG1072, LIM/homeobox protein Awh, Protein arrowhead, awh, ...
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High impact information on Awh

  • Loss-of-function mutations in Arrowhead reduce the number of abdominal histoblasts and salivary gland imaginal ring cells before the proliferative stages of their development [1].
  • Consistent with its role in development, during embryogenesis Arrowhead is expressed in each abdominal segment and in the labial segment [2].
  • When ectopically expressed in imaginal disc cells, Arrowhead causes programmed cell death and loss of corresponding adult structures [2].


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