Gene Review:
Lhx8 - LIM homeobox protein 8
Mus musculus
Synonyms:
L3, LIM homeobox protein 7, LIM/homeobox protein Lhx7, LIM/homeobox protein Lhx8, Lhx7
- Isolated cleft palate in mice with a targeted mutation of the LIM homeobox gene lhx8. Zhao, Y., Guo, Y.J., Tomac, A.C., Taylor, N.R., Grinberg, A., Lee, E.J., Huang, S., Westphal, H. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Identification of the viral genes responsible for growth of strains of reovirus in cultured mouse heart cells. Matoba, Y., Sherry, B., Fields, B.N., Smith, T.W. J. Clin. Invest. (1991)
- Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans. McCarthy, J.S., Wieseman, M., Tropea, J., Kaslow, D., Abraham, D., Lustigman, S., Tuan, R., Guderian, R.H., Nutman, T.B. Infect. Immun. (2002)
- The larval specific lymphatic filarial ALT-2: induction of protection using protein or DNA vaccination. Ramachandran, S., Kumar, M.P., Rami, R.M., Chinnaiah, H.B., Nutman, T., Kaliraj, P., McCarthy, J. Microbiol. Immunol. (2004)
- The homeobox genes Lhx7 and Gbx1 are expressed in the basal forebrain cholinergic system. Asbreuk, C.H., van Schaick, H.S., Cox, J.J., Kromkamp, M., Smidt, M.P., Burbach, J.P. Neuroscience (2002)
- Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Pangas, S.A., Choi, Y., Ballow, D.J., Zhao, Y., Westphal, H., Matzuk, M.M., Rajkovic, A. Proc. Natl. Acad. Sci. U.S.A. (2006)
- The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain. Zhao, Y., Marín, O., Hermesz, E., Powell, A., Flames, N., Palkovits, M., Rubenstein, J.L., Westphal, H. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Expression and role of Lhx8 in murine tooth development. Shibaguchi, T., Kato, J., Abe, M., Tamamura, Y., Tabata, M.J., Liu, J.G., Iwamoto, M., Wakisaka, S., Wanaka, A., Kurisu, K. Arch. Histol. Cytol. (2003)
- Structure and chromosomal localization of a murine LIM/homeobox gene, Lhx8. Kitanaka, J., Takemura, M., Matsumoto, K., Mori, T., Wanaka, A. Genomics (1998)
- Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Grigoriou, M., Tucker, A.S., Sharpe, P.T., Pachnis, V. Development (1998)
- Loss of forebrain cholinergic neurons and impairment in spatial learning and memory in LHX7-deficient mice. Fragkouli, A., Hearn, C., Errington, M., Cooke, S., Grigoriou, M., Bliss, T., Stylianopoulou, F., Pachnis, V. Eur. J. Neurosci. (2005)
- L3, a novel murine LIM-homeodomain transcription factor expressed in the ventral telencephalon and the mesenchyme surrounding the oral cavity. Matsumoto, K., Tanaka, T., Furuyama, T., Kashihara, Y., Mori, T., Ishii, N., Kitanaka, J., Takemura, M., Tohyama, M., Wanaka, A. Neurosci. Lett. (1996)
- The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons. Mori, T., Yuxing, Z., Takaki, H., Takeuchi, M., Iseki, K., Hagino, S., Kitanaka, J., Takemura, M., Misawa, H., Ikawa, M., Okabe, M., Wanaka, A. Eur. J. Neurosci. (2004)
- Comparison of the expression patterns of two LIM-homeodomain genes, Lhx6 and L3/Lhx8, in the developing palate. Zhang, Y., Mori, T., Takaki, H., Takeuch, M., Iseki, K., Hagino, S., Murakawa, M., Yokoya, S., Wanaka, A. Orthodontics & craniofacial research. (2002)
- Fgf-8 determines rostral-caudal polarity in the first branchial arch. Tucker, A.S., Yamada, G., Grigoriou, M., Pachnis, V., Sharpe, P.T. Development (1999)
- Sexually dimorphic effects of the Lhx7 null mutation on forebrain cholinergic function. Fragkouli, A., Stamatakis, A., Zographos, E., Pachnis, V., Stylianopoulou, F. Neuroscience (2006)
- Differential expression of LIM-homeodomain genes in the embryonic murine brain. Matsumoto, K., Tanaka, T., Furuyama, T., Kashihara, Y., Ishii, N., Tohyama, M., Kitanaka, J., Takemura, M., Mori, T., Wanaka, A. Neurosci. Lett. (1996)
- Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection. Mann, M.A., Tyler, K.L., Knipe, D.M., Fields, B.N. Virology (2002)