Gene Review:
loj - logjam
Drosophila melanogaster
Synonyms:
CG10733, Dmel\CG10733, LOJ, l(3)04026, p24
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High impact information on loj
- A newly characterized Drosophila melanogaster gene, logjam (loj), functions in female reproduction by modulating oviposition behavior [1].
- This phenotype can be rescued by the introduction of a transgene expressing the most abundant loj transcript [1].
- As for many genes that specify behavioral outputs, loj is present in the adult central nervous system (CNS) [1].
- Interestingly, it is also observed in vitellogenic egg chambers, suggesting that there may be multiple functions for this gene in egg-laying behavior. loj encodes a predicted protein with homology to the EMP24/GP25 transmembrane components of cytoplasmic vesicles and likely functions in intracellular trafficking [1].
References
- Logjam encodes a predicted EMP24/GP25 protein that is required for Drosophila oviposition behavior. Carney, G.E., Taylor, B.J. Genetics (2003) [Pubmed]
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