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Gene Review:

MEPE - matrix extracellular phosphoglycoprotein

Gallus gallus

Hincke, M.T. et al., Dominguez-Vera, J.M. et al., Mann, K. et al.

Hincke, Gautron, Tsang, McKee, Nys, Mann, Hincke, Nys,

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High impact information on LOC395256

Molecular cloning and ultrastructural localization of the core protein of an eggshell matrix proteoglycan, ovocleidin-116 [1].
Ovocleidin-116 thus is a candidate molecule for the regulation of calcite growth during eggshell calcification [1].
The hypothetical translational product from the open reading frame corresponded to a novel 80-kDa protein, which we have named ovocleidin-116 [1].
Isolation of ovocleidin-116 from chicken eggshells, correction of its amino acid sequence and identification of disulfide bonds and glycosylated Asn [2].
The predominant constituents were ovalbumin and ovotransferrin at the initial phase and lysozyme, ovocleidin-17, ovocalyxin-32, 36- and 21-kDa bands, and ovocleidin-116 at the growth phase [3].

Analytical, diagnostic and therapeutic context of LOC395256

Ultrastructural colloidal gold immunocytochemistry of ovocleidin-116 demonstrated its presence in the organic matrix, in small vesicles found throughout the mineralized palisade layer, and the calcium reserve assembly of the mammillary layer [1].

References

Molecular cloning and ultrastructural localization of the core protein of an eggshell matrix proteoglycan, ovocleidin-116. Hincke, M.T., Gautron, J., Tsang, C.P., McKee, M.D., Nys, Y. J. Biol. Chem. (1999) [Pubmed]
Isolation of ovocleidin-116 from chicken eggshells, correction of its amino acid sequence and identification of disulfide bonds and glycosylated Asn. Mann, K., Hincke, M.T., Nys, Y. Matrix Biol. (2002) [Pubmed]
The effect of avian uterine fluid on the growth behavior of calcite crystals. Dominguez-Vera, J.M., Gautron, J., Garcia-Ruiz, J.M., Nys, Y. Poult. Sci. (2000) [Pubmed]

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