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Gene Review

OLFM1  -  olfactomedin 1

Gallus gallus

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High impact information on OLFM1

  • DFP-treated birds displayed locomotor and neuropathological signs of OPIDN with a no effect level (NOEL) between 25 and 50 micrograms/kg [1].
  • Chickens of group I served as control, while group II birds were given a feed containing 200 ppm of carbendazim, which is considered no observable effect level (NOEL) dose, for a period of 6 months [2].
  • Results clearly indicated down regulation of humoral immunity by carbendazim at NOEL dose [2].


  1. Neurotoxicity of acute and repeated treatments of tabun, paraoxon, diisopropyl fluorophosphate and isofenphos to the hen. Henderson, J.D., Higgins, R.J., Dacre, J.C., Wilson, B.W. Toxicology (1992) [Pubmed]
  2. Down regulation of humoral immunity in chickens due to carbendazim. Singhal, L.K., Bagga, S., Kumar, R., Chauhan, R.S. Toxicology in vitro : an international journal published in association with BIBRA. (2003) [Pubmed]
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