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LFNG  -  LFNG O-fucosylpeptide 3-beta-N...

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High impact information on LFNG

  • Overexpressing Lfng in the paraxial mesoderm abolishes the expression of cyclic genes including endogenous Lfng and leads to defects in segmentation [1].
  • In addition to the sites previously described (Prince et al. [2001] Mech. Dev. 105:175-180; Leve et al. [ 2001] Dev. Genes Evol. 211:493-500), lfng is also expressed in the sensory patches of the inner ear [2].

References

  1. Periodic notch inhibition by lunatic fringe underlies the chick segmentation clock. Dale, J.K., Maroto, M., Dequeant, M.L., Malapert, P., McGrew, M., Pourquie, O. Nature (2003) [Pubmed]
  2. Sequence and embryonic expression of three zebrafish fringe genes: lunatic fringe, radical fringe, and manic fringe. Qiu, X., Xu, H., Haddon, C., Lewis, J., Jiang, Y.J. Dev. Dyn. (2004) [Pubmed]
 
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