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Gene Review

CTSK  -  cathepsin K

Gallus gallus

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High impact information on LOC395818

  • This pattern of expression suggests that JTAP-1 is associated with the transformed phenotype [1].

Analytical, diagnostic and therapeutic context of LOC395818

  • Significantly, using microarray and RT-PCR analyses, we have identified up-regulated genes such as JTAP-1, JAC, and HB-EGF, which belong to the v-Jun transforming pathway [2].


  1. Isolation and cloning of JTAP-1: a cathepsin like gene upregulated in response to V-Jun induced cell transformation. Hadman, M., Gabos, L., Loo, M., Sehgal, A., Bos, T.J. Oncogene (1996) [Pubmed]
  2. Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: a converging transforming pathway for avian oncoviruses. Levy, A.M., Gilad, O., Xia, L., Izumiya, Y., Choi, J., Tsalenko, A., Yakhini, Z., Witter, R., Lee, L., Cardona, C.J., Kung, H.J. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
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