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Gene Review:

ARHGDIG - Rho GDP dissociation inhibitor (GDI) gamma

Homo sapiens

Synonyms: RHOGDI-3, Rho GDI 3, Rho GDP-dissociation inhibitor 3, Rho-GDI gamma

Jiang, W.G. et al., Adra, C.N. et al.

Jiang, Watkins, Lane, Cunnick, Douglas-Jones, Mokbel, Mansel, Adra, Iyengar, Syed, Kanaan, Rilo, Yu, Kheraj, Lin, Horiuchi, Khan, Weremowicz, Lim, Morton, Higgs,

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Disease relevance of ARHGDIG

Patients with recurrent disease, with metastasis or who died of breast cancer, also exhibited higher levels of Rho-6 but lower levels of Rho-GDI-gamma [1].

High impact information on ARHGDIG

Node-positive tumors have significantly higher levels of Rho-C and Rho-G, and lower levels of Rho-GDI and Rho-GDI-gamma transcripts, than do node-negative tumors [1].
Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3 [2].

References

Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers. Jiang, W.G., Watkins, G., Lane, J., Cunnick, G.H., Douglas-Jones, A., Mokbel, K., Mansel, R.E. Clin. Cancer Res. (2003) [Pubmed]
Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3. Adra, C.N., Iyengar, A.R., Syed, F.A., Kanaan, I.N., Rilo, H.L., Yu, W., Kheraj, R., Lin, S.R., Horiuchi, T., Khan, S., Weremowicz, S., Lim, B., Morton, C.C., Higgs, D.R. Genomics (1998) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

ARHGDIG	Bos taurus
ARHGDIG	Canis lupus familiaris
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ARHGDIG	Macaca mulatta
Arhgdig	Mus musculus
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Arhgdig	Rattus norvegicus
arhgdig	Xenopus (Silurana) tropicalis

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