Gene Review:
darmin - darmin
Xenopus laevis
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High impact information on darmin
- Xenopus Darmin showed zygotic expression in the early endoderm and later became restricted to the midgut [1].
- In an unbiased secretion cloning screen of Xenopus gastrula embryos we isolated a novel gene, designated Darmin [1].
- Darmin encodes a secreted protein of 56 kDa containing a peptidase M20 domain characteristic of the glutamate carboxypeptidase group of zinc metalloproteases [1].
Biological context of darmin
- The endoderm-specific expression of Darmin makes this gene a useful marker for the study of endoderm development [1].
References
- Darmin is a novel secreted protein expressed during endoderm development in Xenopus. Pera, E.M., Martinez, S.L., Flanagan, J.J., Brechner, M., Wessely, O., De Robertis, E.M. Gene Expr. Patterns (2003) [Pubmed]
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