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Gene Review:

tpx - thiol peroxidase

Escherichia coli UTI89

Kim, Y.H. et al.

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Disease relevance of tpx

To the best of our knowledge, this is the first mutational study to show the contribution of sodC and tpx gene products to the formation of an E. coli O157:H7 biofilm [1].

High impact information on tpx

An analysis of their growth phase-dependent gene expression indicated that a high level of the sodC expression occurred during the stationary phase and that the expression of the tpx gene was strongly induced only during the exponential growth phase [1].
This study examined the role of the periplasmic oxidative defense proteins, copper, zinc superoxide dismutase (SodC), and thiol peroxidase (Tpx), from the Shiga toxin-producing Escherichia coli O157:H7 (STEC) in the formation of biofilms [1].

References

The role of periplasmic antioxidant enzymes (superoxide dismutase and thiol peroxidase) of the Shiga toxin-producing Escherichia coli O157:H7 in the formation of biofilms. Kim, Y.H., Lee, Y., Kim, S., Yeom, J., Yeom, S., Seok Kim, B., Oh, S., Park, S., Jeon, C.O., Park, W. Proteomics (2006) [Pubmed]

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