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Gene Review:

GALK1 - galactokinase 1

Canis lupus familiaris

Kliegman, R.M. et al., Sidjanin, D.J. et al., Wilson, D. et al.

Sidjanin, McElwee, Miller, Aguirre,

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Disease relevance of GALK1

Cloning of canine galactokinase (GALK1) and evaluation as a candidate gene for hereditary cataracts in Labrador retrievers [1].

High impact information on GALK1

The observed increase in glycogen synthesis and reduced systemic glucose appearance after galactose alimentation could not be accounted for by the previously proposed excess of galactokinase over glucokinase activities when the latter enzyme was assayed at saturation [2].
The genes for galactokinase and uridine monophosphatase-2 are syntenic in the dog (Canis familiaris) [3].

References

Cloning of canine galactokinase (GALK1) and evaluation as a candidate gene for hereditary cataracts in Labrador retrievers. Sidjanin, D.J., McElwee, J., Miller, B., Aguirre, G.D. Anim. Genet. (2005) [Pubmed]
Galactose assimilation in pups of diabetic canine mothers. Kliegman, R.M., Morton, S. Diabetes (1987) [Pubmed]
The genes for galactokinase and uridine monophosphatase-2 are syntenic in the dog (Canis familiaris). Wilson, D., Adari, H. Biochem. Genet. (1987) [Pubmed]

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AgaP_AGAP002914	Anopheles gambiae str. PEST
GalAK	Arabidopsis thaliana
GALK1	Bos taurus
galk1	Danio rerio
GALK1	Gallus gallus
GALK1	Homo sapiens
GALK1	Macaca mulatta
Galk1	Mus musculus
Os04g0608100	Oryza sativa Japonica Group
GALK1	Pan troglodytes
Galk1	Rattus norvegicus
galk1	Xenopus (Silurana) tropicalis

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