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Gene Review

YY2  -  YY2 transcription factor

Homo sapiens

Synonyms: Transcription factor YY2, YY-2, Yin and yang 2, ZNF631, Zinc finger protein 631
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High impact information on YY2

  • A sequence analysis of this novel protein, YY2, revealed an overall 65% identity in the DNA sequence and a 56% identity in protein sequence compared with human YY1 [1].
  • Rapid evolution of a recently retroposed transcription factor YY2 in mammalian genomes [2].
  • Our results indicate that YY2 is a retroposed copy of YY1 that has been inserted into another gene locus named Mbtps2 (membrane-bound transcription factor protease site 2) [2].

Biological context of YY2


Analytical, diagnostic and therapeutic context of YY2


  1. Molecular cloning and functional characterization of the transcription factor YY2. Nguyen, N., Zhang, X., Olashaw, N., Seto, E. J. Biol. Chem. (2004) [Pubmed]
  2. Rapid evolution of a recently retroposed transcription factor YY2 in mammalian genomes. Luo, C., Lu, X., Stubbs, L., Kim, J. Genomics (2006) [Pubmed]
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