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Gene Review

PEK  -  pancreatic eIF-2alpha kinase

Drosophila melanogaster

Synonyms: CG2087, DPERK, DmPEK, Dmel\CG2087, DpERK, ...
 
 
 
 
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High impact information on PEK

  • Furthermore, the stable complexes between wild-type DPERK and DPERK-K671R mutant were mediated through the N terminus of the proteins and exhibited an in vitro eIF2alpha kinase activity [1].
  • During embryogenesis, DPERK expression becomes concentrated in the endodermal cells of the gut and in the germ line precursor cells [1].

References

  1. Functional characterization of Drosophila melanogaster PERK eukaryotic initiation factor 2alpha (eIF2alpha) kinase. Pomar, N., Berlanga, J.J., Campuzano, S., Hernández, G., Elías, M., de Haro, C. Eur. J. Biochem. (2003) [Pubmed]
 
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