Gene Review:
eIF-2alpha - eukaryotic translation Initiation Factor...
Drosophila melanogaster
Synonyms:
CG9946, Dmel\CG9946, EIF-2alpha, Eif2alpha, Eukaryotic translation initiation factor 2 subunit 1, ...
- Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster. Qu, S., Perlaky, S.E., Organ, E.L., Crawford, D., Cavener, D.R. Gene Expr. (1997)
- Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2. Asano, K., Krishnamoorthy, T., Phan, L., Pavitt, G.D., Hinnebusch, A.G. EMBO J. (1999)
- Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2. Kubota, H., Ota, K., Sakaki, Y., Ito, T. J. Biol. Chem. (2001)
- Characterization of the initiation factor eIF2B and its regulation in Drosophila melanogaster. Williams, D.D., Pavitt, G.D., Proud, C.G. J. Biol. Chem. (2001)
- Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology To yeast GCN2 protein kinase. Santoyo, J., Alcalde, J., Méndez, R., Pulido, D., de Haro, C. J. Biol. Chem. (1997)
- Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase. Olsen, D.S., Jordan, B., Chen, D., Wek, R.C., Cavener, D.R. Genetics (1998)
- A key transcription factor for eukaryotic initiation factor-2 alpha is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development. Efiok, B.J., Chiorini, J.A., Safer, B. J. Biol. Chem. (1994)
- Protein synthesis in Drosophila melanogaster embryos. Two mechanisms for guanine nucleotide exchange on eukaryotic initiation factor 2. Mateu, M.G., Sierra, J.M. Eur. J. Biochem. (1987)
- Cloning and characterization of an eukaryotic initiation factor-2alpha kinase from the silkworm, Bombyx mori. Prasad, M.D., Han, S.J., Nagaraju, J., Lee, W.J., Brey, P.T. Biochim. Biophys. Acta (2003)
- Functional characterization of Drosophila melanogaster PERK eukaryotic initiation factor 2alpha (eIF2alpha) kinase. Pomar, N., Berlanga, J.J., Campuzano, S., Hernández, G., Elías, M., de Haro, C. Eur. J. Biochem. (2003)
- Heat shock effects on phosphorylation of protein synthesis initiation factor proteins eIF-4E and eIF-2 alpha in Drosophila. Duncan, R.F., Cavener, D.R., Qu, S. Biochemistry (1995)
- The 90-kilodalton peptide of the heme-regulated eIF-2 alpha kinase has sequence similarity with the 90-kilodalton heat shock protein. Rose, D.W., Wettenhall, R.E., Kudlicki, W., Kramer, G., Hardesty, B. Biochemistry (1987)