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Gene Review

Ama  -  Amalgam

Drosophila melanogaster

Synonyms: AMA, BG:DS00276.6, CG2198, CT7244, Dmel\CG2198, ...
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High impact information on Ama

  • Furthermore, AMA is necessary for NRT-expressing cells both to aggregate with themselves and to associate with embryonic primary culture cells [1].

Biological context of Ama


Associations of Ama with chemical compounds


Other interactions of Ama

  • Amalgam (Ama) is a secreted protein that interacts with the transmembrane protein Neurotactin (Nrt) to promote cell:cell adhesion [2].


  1. Amalgam is a ligand for the transmembrane receptor neurotactin and is required for neurotactin-mediated cell adhesion and axon fasciculation in Drosophila. Frémion, F., Darboux, I., Diano, M., Hipeau-Jacquotte, R., Seeger, M.A., Piovant, M. EMBO J. (2000) [Pubmed]
  2. Interactions between the secreted protein Amalgam, its transmembrane receptor Neurotactin and the Abelson tyrosine kinase affect axon pathfinding. Liebl, E.C., Rowe, R.G., Forsthoefel, D.J., Stammler, A.L., Schmidt, E.R., Turski, M., Seeger, M.A. Development (2003) [Pubmed]
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