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Gene Review

ING1  -  inhibitor of growth family, member 1

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High impact information on ING1

  • Furthermore, the expression of ING1 is induced in senescent cells and antisense ING1 extends the proliferative life span of primary human fibroblasts [1].
  • In addition, we show that both silencing domains of ING1 are involved in cell cycle control, as measured by inhibition of colony formation of immortalized cells and by thymidine incorporation of primary human diploid fibroblasts (HDF) [1].


  1. Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras. Goeman, F., Thormeyer, D., Abad, M., Serrano, M., Schmidt, O., Palmero, I., Baniahmad, A. Mol. Cell. Biol. (2005) [Pubmed]
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