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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CDK6  -  cyclin-dependent kinase 6

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High impact information on CDK6

  • Immunoblot and immunofluorescence analyses revealed that cdk6-infected astrocytes had an altered expression profile of known markers of glial differentiation [1].
  • Several other differences in cdk4- and cdk6-infected cells were noted, including differential binding to a subset of cell-cycle inhibitor proteins and a distinct pattern of subcellular localization of these kinases [1].

References

  1. Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes. Ericson, K.K., Krull, D., Slomiany, P., Grossel, M.J. Mol. Cancer Res. (2003) [Pubmed]
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