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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

AP-1sigma  -  Adaptor Protein complex 1, sigma subunit

Drosophila melanogaster

Synonyms: AP-1[sigma], AP-1sigma1, AP1sigma1, CG5864, Dmel\CG5864, ...
 
 
 
 
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High impact information on AP-1sigma

  • Caffeine-responsive sequences are not clustered at one place; they appear to be dispersed in -983/-126 and -761/-109 regions of Cyp6a2 and Cyp6a8 genes which also contain many binding sites for activator protein 1 (AP1) and cyclic AMP response element binding protein (CRE-BP) [1].

References

  1. Induction of two cytochrome P450 genes, Cyp6a2 and Cyp6a8, of Drosophila melanogaster by caffeine in adult flies and in cell culture. Bhaskara, S., Dean, E.D., Lam, V., Ganguly, R. Gene (2006) [Pubmed]
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