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Gene Review

pasha  -  partner of drosha

Drosophila melanogaster

Synonyms: CG1800, DGCR8, Dmel\CG1800, PASHA, Pasha, ...
 
 
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High impact information on pasha

  • The Drosha-Pasha/DGCR8 complex in the nucleus cleaves pri-miRNAs to release hairpin-shaped precursor miRNAs (pre-miRNAs) [1].
 

Biological context of pasha

References

  1. Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. Saito, K., Ishizuka, A., Siomi, H., Siomi, M.C. PLoS Biol. (2005) [Pubmed]
  2. Processing of primary microRNAs by the Microprocessor complex. Denli, A.M., Tops, B.B., Plasterk, R.H., Ketting, R.F., Hannon, G.J. Nature (2004) [Pubmed]
 
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